2,6-Dichloro-4-nitroaniline Dichloran · CAS 99-30-9

What is 2,6-Dichloro-4-nitroaniline?

2,6-Dichloro-4-nitroaniline is a benzene ring carrying a primary amine at the 1-position, chlorine atoms at the 2- and 6-positions, and a nitro group at the 4-position, formula C₆H₄Cl₂N₂O₂. It is supplied as a yellow powder or crystalline solid.

The molecule is best known under its common name, Dichloran (also written DCNA), where it is the active ingredient in a long-established class of fungicide formulations used to control Botrytis and related fungi on fruit, vegetable and ornamental crops. The same molecule, at the purity and documentation your application needs, is also supplied as a dyestuff and pharmaceutical intermediate.

Commercially it is produced by chlorinating 4-nitroaniline under controlled conditions to introduce the two chlorine atoms symmetrically around the amine.

Handling follows standard precautions for a toxic nitroaromatic intermediate — chemical-resistant gloves and eye protection, adequate ventilation, and storage away from incompatible materials such as strong oxidisers.

Why 2,6-Dichloro-4-nitroaniline specifically

• A proven, well-characterised molecule. Decades of use as Dichloran mean its chemistry, toxicology and handling profile are extensively documented.
• Dual-purpose supply. The same CAS number serves as a dye/pharma intermediate and as an agrochemical active, depending on the grade and documentation you order against.
• Symmetric chlorine placement. The 2,6-dichloro pattern around the amine gives a specific, reproducible reactivity that downstream formulators and chemists rely on.
• Established fungicidal activity. Where registered, used in post-harvest and field formulations targeting Botrytis cinerea and related fungal pathogens.

How 2,6-Dichloro-4-nitroaniline is Manufactured

2,6-Dichloro-4-nitroaniline is produced by chlorinating 4-nitroaniline under controlled conditions to place chlorine symmetrically at the 2- and 6-positions.

• Chlorination. 4-Nitroaniline is chlorinated under controlled temperature and pH to direct substitution to the 2- and 6-positions.
• Workup. The crude product is separated from the reaction liquor and washed.
• Crystallisation. The product is purified by crystallisation, commonly from aqueous ethanol, to the target assay and melting-point specification.
• Quality release and packing. Assay, melting point and appearance are confirmed against specification before the batch is packed and released.

Typical Commercial Specification

Figures below are representative of commercial-grade 2,6-Dichloro-4-nitroaniline. Tell us your downstream use and the grade you need, and we will advise on the specification to order against.

Physical & Chemical Properties

Behaviour in the process

2,6-Dichloro-4-nitroaniline's reactivity pattern is what both agrochemical formulators and dye/pharma intermediate buyers are purchasing:

• Free amine reactivity. The amine is available for acylation, diazotisation or further condensation chemistry.
• Stable, symmetric substitution. The 2,6-dichloro pattern around the amine is sterically and electronically well-defined, giving reproducible downstream behaviour.
• Thermal stability. Stable under normal storage conditions away from strong oxidisers and reducing agents.

2,6-Dichloro-4-nitroaniline and Related Intermediates

Choosing between chlorinated nitroaniline intermediates comes down to the substitution pattern and the reduced or non-reduced form the target synthesis needs.

Stated plainly: a formulation or synthesis built around Dichloran needs this specific molecule — the related chloroaniline and chloronitrobenzene intermediates have different reactivity and are not drop-in substitutes.

Industries We Supply 2,6-Dichloro-4-nitroaniline To

The same molecule feeds an agrochemical formulator buying the Dichloran active, a dye-intermediate manufacturer and a pharmaceutical intermediate producer. What changes is the purity grade, formulation support and the documentation each requires.

Where 2,6-Dichloro-4-nitroaniline is Used

In downstream processing

As a fungicide active, 2,6-dichloro-4-nitroaniline is formulated into wettable powders, dusts or suspension concentrates by registered formulators. As a dye or pharma intermediate, its free amine is carried through acylation, diazotisation or condensation chemistry to build the target molecule.

Quality Control & Testing

Every lot is released against a batch-specific Certificate of Analysis, with melting point reported alongside the main assay as a sensitive indicator of purity for this molecule.

• Assay — by HPLC/GC, the primary grade measure, reported against the technical or fine-chemical specification ordered.
• Melting point — a narrow, well-characterised range for this molecule; a broadened range is a fast indicator of impurity.
• Appearance — colour and physical form reported because they are sensitive to processing and storage history.

Common Process Problems & Likely Causes

Packaging, Storage & Shipping

• Standard packing. Multi-ply paper or HDPE-lined bags and fibre drums, typically 25 kg net, with bulk-bag formats on contract supply.
• Moisture protection. Keep bags sealed and stored off the floor to limit moisture pickup and caking.
• Temperature control. Store in a cool, dry, well-ventilated area away from direct sun and heat; some grades are recommended for refrigerated storage — confirm against your COA.
• Material compatibility. Avoid contact with strong oxidisers and strong reducing agents.
• Transport classification. Commonly shipped under UN 2237, Class 6.1, packing group III. Confirm the correct entry and packing group against your own current SDS before shipping.

Hazards & Safe Handling

2,6-Dichloro-4-nitroaniline is harmful if swallowed and may cause an allergic skin reaction, and is toxic to aquatic life with long-lasting effects. Standard precautions for a toxic nitroaromatic intermediate and good laboratory and plant practice apply throughout handling.

• Skin and eye contact. Chemical-resistant gloves and goggles are standard practice for this intermediate; rinse thoroughly with water on contact.
• Inhalation. Use adequate ventilation when handling, particularly when transferring or opening bags.
• PPE. Chemical-resistant gloves, safety goggles and a suitable dust mask or respirator where dust exposure is a concern.
• Environment. Toxic to aquatic life with long-lasting effects; avoid uncontrolled release to water and follow local effluent rules.

Regulatory & Compliance Notes

2,6-Dichloro-4-nitroaniline is a long-registered industrial and agrochemical intermediate. Because obligations differ sharply by territory and by whether the material is sold as a chemical intermediate or as (or within) a plant-protection product, the notes below are orientation rather than legal advice.

• GHS classification. Classified as harmful if swallowed, as a suspected skin sensitiser, and as toxic to aquatic life with long-lasting effects; the SDS carries the full hazard statements for your grade.
• Agrochemical registration. Where supplied or formulated as the fungicide active Dichloran, local plant-protection-product registration, labelling, approved crops and maximum residue limits apply and vary by country — confirm with your regulatory team before marketing it for that use.
• REACH and chemical inventories. Registered under EU REACH and listed on major chemical inventories.
• Dangerous goods transport. Commonly shipped under UN 2237 (Nitroanilines), Class 6.1, packing group III. Confirm the correct entry and packing group with your logistics/EHS team against your current SDS before shipping.
• HS code. Commonly declared under the aromatic amine derivatives heading; confirm the exact tariff line with your customs broker for your jurisdiction.

We Supply 2,6-Dichloro-4-nitroaniline Worldwide

Chelora Chemicals is a supplier and export partner, not a single-plant trader. We ship 2,6-Dichloro-4-nitroaniline from India and from partner sources to customers across Asia, Europe, the Middle East, Africa, and North and South America, handling the export documentation and freight so the material arrives ready to use.

• Incoterms. EXW, FOB, CIF, CFR and DAP quoted to suit your purchasing terms and freight arrangements.
• Ports. Regular shipments through Nhava Sheva (JNPT) and Mundra, with other ports arranged as routing allows.
• Documentation. Commercial invoice, packing list, certificate of origin, COA and SDS issued as a complete set.
• Flexible volumes. From trial quantities up to repeat bulk shipments on a supply contract.

Buying 2,6-Dichloro-4-nitroaniline from Chelora

We are an independent sourcing and supply partner. For this product that means settling three things at enquiry: whether you need technical or fine-chemical grade, the packing format, and the quantity you are buying.

• Documentation on every lot. Batch-specific COA with assay, melting point and appearance, plus the current SDS.
• Analysis before commitment. Representative analysis shared ahead of a commercial order so your lab or regulatory team can qualify the material.
• Quantities. Trial quantities through to larger bulk shipments on contract supply.
• Inspection. Independent third-party inspection available at loading when the contract requires it.
• Related intermediates. 2,5-Dichloro Nitro Benzene, 2,6-Dichloroaniline and other chlorinated nitro and amino intermediates alongside this product from one supplier.

How ordering works

• Send the enquiry. Grade (technical or fine-chemical), quantity, destination port and the Incoterm you buy on.
• We quote. Price, lead time, packing format and a sample COA, normally within one working day.
• Qualify the supply. For first orders or formulation-/pharma-grade applications, we share the analysis so your technical team can sign off before you commit.
• Confirm the order. Proforma invoice issued; payment terms agreed against the volume and the relationship.
• Ship and document. Packed, labelled and loaded with the full export document set, and tracked through to arrival.

Related Nitro & Chloro Intermediates