2-Hydrazino-4-methylbenzothiazole HMBT · CAS 20174-68-9
Chelora Chemicals is a supplier of 2-Hydrazino-4-methylbenzothiazole, the benzothiazole hydrazine best known as the direct precursor to tricyclazole. The hydrazine arm and the ring nitrogen together close the triazole ring in a single cyclisation step. Every consignment leaves with a batch-specific COA and the current SDS.
Also known as: HMBT, 4-Methyl-2-hydrazinobenzothiazole, 4-Methyl-2-benzothiazolehydrazine, 2-Hydrazinyl-4-methylbenzo[d]thiazole, 2-Hydrazino-4-methyl-1,3-benzothiazole
Request a quotation
Price, lead time and a sample COA for 2-Hydrazino-4-methylbenzothiazole, usually within one working day. We ship worldwide.
Request a Quote Email the DeskDocumentation
- Batch-specific COA (assay, melting range, moisture)
- Safety Data Sheet (SDS)
- UN 2811 dangerous-goods transport documents
- Third-party inspection on request
- Certificate of origin
What is 2-Hydrazino-4-methylbenzothiazole?
2-Hydrazino-4-methylbenzothiazole is a benzothiazole ring carrying a hydrazine group at the 2-position and a methyl group at the 4-position, formula C₈H₉N₃S. In pure form it is a near-white to pale yellow crystalline solid; technical-grade material is typically a light grey to beige powder.
The chemistry it enables is specific and well defined. The hydrazine arm at C-2 sits right next to the ring nitrogen, and that arrangement is exactly what a triazole ring closure needs — react it with a one-carbon source such as formic acid or an orthoester and the fused triazolobenzothiazole forms directly.
That is why the overwhelming majority of commercial volume goes into tricyclazole, the rice blast fungicide. The 4-methyl group is not incidental: it is the methyl that appears in the finished active.
Handling follows standard precautions for a substituted hydrazine. It is harmful if swallowed and irritating to skin and eyes, and should be handled with gloves, eye protection and dust control.
Why 2-Hydrazino-4-methylbenzothiazole specifically
- A pre-built cyclisation motif. Hydrazine at C-2 adjacent to the ring nitrogen gives a one-step route to the fused triazole.
- The methyl is already placed. The 4-methyl group carries straight into the target active, so no late-stage methylation is needed.
- A crystalline, filterable solid. Easy to charge, easy to assay and stable under ordinary storage.
- Established agrochemical supply chain. Routinely manufactured at commercial scale for fungicide production.
How 2-Hydrazino-4-methylbenzothiazole is Manufactured
The commercial route builds the benzothiazole ring from an ortho-substituted toluidine and then installs the hydrazine at C-2.
- Ring formation. A methyl-substituted aniline is converted to the corresponding 4-methylbenzothiazole bearing a displaceable group at the 2-position.
- Hydrazinolysis. That 2-position is displaced by hydrazine hydrate under controlled temperature to install the hydrazine arm.
- Isolation. The product crystallises on cooling and is filtered, washed free of excess hydrazine and inorganic salts, and dried.
- Quality release and packing. Assay, melting range and moisture are confirmed against specification before the batch is packed and released.
Typical Commercial Specification
Figures below are representative of commercial-grade 2-hydrazino-4-methylbenzothiazole. Tell us your downstream route and the grade you need, and we will advise on the specification to order against.
| Parameter | Typical Value |
|---|---|
| Appearance | Pale yellow to beige-grey crystalline powder |
| Assay | 98% min — technical grades from 95% |
| Melting range | To grade, typically a narrow band in the 160s °C |
| Moisture | Low, to grade |
| Residual hydrazine | Trace levels to grade |
Physical & Chemical Properties
| Property | Value |
|---|---|
| Chemical formula | C₈H₉N₃S |
| Molecular weight | 179.24 g/mol |
| Appearance | Pale yellow to beige crystalline powder |
| Physical state | Solid at room temperature |
| Solubility | Insoluble in water; soluble in hot alcohols and polar organic solvents |
| Storage | Cool, dry, sealed, away from light |
| Incompatibilities | Strong oxidisers, strong acids, nitrous acid sources |
| Stability | Stable under normal storage; hydrazines oxidise on prolonged air exposure |
Behaviour in the process
The hydrazine arm is what the molecule is bought for:
- Triazole ring closure. Condensation with formic acid, orthoesters or equivalent one-carbon sources closes the fused triazole directly.
- Hydrazone formation. Reacts readily with aldehydes and ketones, which is the basis of its analytical uses.
- Oxidative sensitivity. Hydrazines darken on prolonged air exposure; keep containers sealed.
- Thermal behaviour. Stable under normal storage, but avoid heating with strong oxidisers.
2-Hydrazino-4-methylbenzothiazole and Related Heterocycles
Choosing between benzothiazole intermediates comes down to which substituent pattern the target molecule needs on the ring.
| Material | Ring substitution | When it is the right choice |
|---|---|---|
| 2-Hydrazino-4-methylbenzothiazole | 2-Hydrazino, 4-methyl | Tricyclazole and other 4-methyl triazolobenzothiazole routes |
| 2-Hydrazinobenzothiazole | 2-Hydrazino, unsubstituted ring | Routes where no ring methyl is wanted |
| 2-Hydrazino-6-methylbenzothiazole | 2-Hydrazino, 6-methyl | Different ring isomer — not interchangeable with the 4-methyl |
| 2-Amino-4-methylbenzothiazole | 2-Amino, 4-methyl | Amide and urea chemistry rather than hydrazone or triazole formation |
Stated plainly: the position of that ring methyl matters. The 6-methyl isomer is a different compound with a different CAS number and will give you a different product.
Industries We Supply 2-Hydrazino-4-methylbenzothiazole To
The same intermediate feeds a technical-grade fungicide plant and a medicinal-chemistry laboratory. What changes is the scale, the impurity limits and the documentation each requires.
Where 2-Hydrazino-4-methylbenzothiazole is Used
In downstream functionalisation
The characteristic step is a condensation and ring closure in one: the terminal hydrazine nitrogen picks up a one-carbon unit, then the ring nitrogen closes onto it to form the fused triazole. The 4-methyl group takes no part in that chemistry — it is simply carried through to the finished molecule, which is why its position on the ring is non-negotiable.
Need a specific purity grade?
Tell us the purity grade you need, your downstream chemistry, the packing format you can receive and the annual quantity. We will come back with a price, a lead time and a sample COA.
Quality Control & Testing
Every lot is released against a batch-specific Certificate of Analysis, with moisture and residual hydrazine reported alongside the main assay because both affect the cyclisation step.
- Assay — the primary grade measure, with technical and high-purity grades available.
- Melting range — a practical purity check on a crystalline solid and the fastest incoming-goods test.
- Moisture — reported because wet material affects both charging accuracy and the condensation.
- Residual hydrazine — reported because it is both a process and a regulatory consideration.
Common Process Problems & Likely Causes
| Symptom | Likely cause | What to check |
|---|---|---|
| Incomplete cyclisation | Wet material or unreacted precursor in the feed | Moisture and assay figures on the COA |
| Low or broad melting range | Residual solvent, moisture or precursor carryover | Loss on drying and melting range on the COA |
| Darkened or grey material | Air oxidation of the hydrazine on storage | Lot age, container seal; confirm assay before rejecting |
| Unexpected isomeric product | Wrong ring isomer supplied or specified | CAS number on the COA — 4-methyl and 6-methyl are different compounds |
Packaging, Storage & Shipping
- Standard packing. Lined bags or fibre drums, typically 25 kg net, with larger bulk formats on contract supply.
- Oxidation protection. Keep containers tightly sealed and away from light; hydrazines darken on prolonged air exposure.
- Temperature control. Store in a cool, dry, well-ventilated area away from direct sun and heat.
- Material compatibility. Keep away from strong oxidisers, strong acids and nitrous acid sources.
- Transport classification. Commonly shipped under UN 2811, Class 6.1, PG III — confirm against your own current SDS before shipping.
Hazards & Safe Handling
2-Hydrazino-4-methylbenzothiazole is harmful if swallowed and irritating to skin and eyes. Substituted hydrazines as a class warrant careful handling, so work to your own current SDS rather than to general powder-handling practice.
- Skin and eye contact. Gloves and safety goggles are standard; rinse thoroughly with water on contact.
- Dust. Avoid generating dust when charging reactors; use local exhaust ventilation and a suitable dust mask.
- PPE. Chemical-resistant gloves, safety goggles and respiratory protection where airborne powder is a concern.
- Environment. Avoid uncontrolled release to water and follow local effluent rules.
Regulatory & Compliance Notes
2-Hydrazino-4-methylbenzothiazole is a specialty agrochemical and fine-chemical intermediate. Because obligations differ by territory and use, the notes below are orientation rather than legal advice.
- GHS classification. Commonly classified as harmful if swallowed and as a skin and eye irritant; the SDS carries the full hazard statements for your grade.
- Chemical inventories. Inventory status varies by territory — confirm before import, particularly for commercial quantities.
- Agrochemical registration. Where this feeds a registered fungicide, your dossier will specify impurity limits including residual hydrazine. Tell us those limits at enquiry.
- HS code. Commonly declared under the heterocyclic compounds heading covering benzothiazole ring systems; confirm the exact tariff line with your customs broker.
We Supply 2-Hydrazino-4-methylbenzothiazole Worldwide
Chelora Chemicals is a supplier and export partner, not a single-plant trader. We ship 2-Hydrazino-4-methylbenzothiazole from India and from partner sources to customers across Asia, Europe, the Middle East, Africa, and North and South America, handling the export documentation and freight so the material arrives ready to use.
- Incoterms. EXW, FOB, CIF, CFR and DAP quoted to suit your purchasing terms and freight arrangements.
- Ports. Regular shipments through Nhava Sheva (JNPT) and Mundra, with other ports arranged as routing allows.
- Documentation. Commercial invoice, packing list, certificate of origin, COA and SDS issued as a complete set.
- Flexible volumes. From trial quantities up to repeat bulk shipments on a supply contract.
Buying 2-Hydrazino-4-methylbenzothiazole from Chelora
We are an independent sourcing and supply partner. For this product that means settling three things at enquiry: the assay grade your application needs, the moisture and residual-hydrazine limits, and the quantity you are buying.
- Documentation on every lot. Batch-specific COA with assay, melting range and moisture, plus the current SDS.
- Analysis before commitment. Representative analysis shared ahead of a commercial order so your lab can qualify the material.
- Quantities. Trial quantities through to repeat 25 kg bag shipments on contract supply.
- Inspection. Independent third-party inspection available at loading when the contract requires it.
- Related intermediates. Methyl-substituted anilines and other agrochemical building blocks alongside this product from one supplier.
How ordering works
- Send the enquiry. Assay grade, moisture limit, quantity, destination port and the Incoterm you buy on.
- We quote. Price, lead time, packing format and a sample COA, normally within one working day.
- Qualify the supply. For first orders or registered-active applications, we share the analysis so your technical team can sign off before you commit.
- Confirm the order. Proforma invoice issued; payment terms agreed against the volume and the relationship.
- Ship and document. Packed, labelled and loaded with the full export document set, and tracked through to arrival.
2-Hydrazino-4-methylbenzothiazole — Common Questions
The questions our technical desk is asked most often about 2-Hydrazino-4-methylbenzothiazole. If yours isn't here, call or email and you will reach someone who knows the chemistry.
What is the CAS number of 2-Hydrazino-4-methylbenzothiazole?
The CAS number for 2-Hydrazino-4-methylbenzothiazole (HMBT) is 20174-68-9. Its molecular formula is C₈H₉N₃S with a molecular weight of 179.24 g/mol.
What is 2-Hydrazino-4-methylbenzothiazole used for?
Its principal commercial use is as the intermediate for tricyclazole, the rice blast fungicide. It is also used more generally to build fused triazole scaffolds and as a derivatising reagent for carbonyl compounds.
Why is the hydrazine group important?
Because it sits next to the ring nitrogen. That arrangement lets a one-carbon source close a fused triazole ring in a single step, which is the whole basis of the tricyclazole route.
How does it differ from the 6-methyl isomer?
The methyl sits on a different ring position, giving a different compound with its own CAS number. They are not interchangeable — check the CAS on the COA, not just the name.
How is 2-Hydrazino-4-methylbenzothiazole manufactured?
By forming the 4-methylbenzothiazole ring with a displaceable group at the 2-position, then treating it with hydrazine hydrate to install the hydrazine arm, followed by crystallisation and drying.
Is 2-Hydrazino-4-methylbenzothiazole hazardous?
It is harmful if swallowed and irritating to skin and eyes, and substituted hydrazines as a class warrant careful handling. Refer to the current SDS for your grade for the complete classification.
What is the UN number and transport classification?
Commonly shipped under UN 2811 (Toxic solid, organic, n.o.s.), Class 6.1, Packing Group III. Confirm the correct entry and packing group against your own current SDS before relying on it for shipping documentation.
What is the appearance and melting behaviour?
Pure material is a near-white to pale yellow crystalline solid; technical grade is typically light grey to beige. The melting range sits in the 160s °C — confirm against your own supplier's COA for batch-specific figures.
Why has my material turned grey in storage?
Hydrazines oxidise slowly on air exposure and darken as they do. Check the container seal and the lot age, and judge the material on its assay before rejecting it on colour.
How should 2-Hydrazino-4-methylbenzothiazole be stored?
In sealed containers, cool, dry and away from light, heat, strong oxidisers and strong acids.
What purity grades do you offer?
Technical grades from around 95% and high-purity grades at 98% minimum, with melting range, moisture and residual hydrazine reported on the COA.
What packing sizes and order quantities are available?
Lined bags or fibre drums, typically 25 kg net, with larger bulk formats available on contract supply. Orders run from trial quantities up to repeat bulk loads.
Ready to source 2-Hydrazino-4-methylbenzothiazole?
Send us your purity requirement and annual volume. You will get a price, a realistic lead time and a sample COA from someone who understands what the material has to do in your process — delivered anywhere in the world.