2,5-Dichloro Nitro Benzene 2,5-DCNB · CAS 89-61-2

What is 2,5-Dichloro Nitro Benzene?

2,5-Dichloro Nitro Benzene, also called 1,4-dichloro-2-nitrobenzene, is a benzene ring carrying two chlorine atoms at the 2- and 5-positions and a nitro group at the 1-position, formula C₆H₃Cl₂NO₂. It is supplied as yellow to brown flakes or chunks at ambient temperature.

Its value as an intermediate comes from the specific arrangement of the two chlorines relative to the nitro group, which sets up the ring for the substitution and reduction chemistry that downstream dye, agrochemical and pharmaceutical routes are built around.

Commercially it is produced by nitrating 1,4-dichlorobenzene with mixed acid under controlled temperature, giving essentially pure 2,5-Dichloro Nitro Benzene in high yield.

Handling follows standard precautions for a nitro-aromatic intermediate — chemical-resistant gloves and eye protection, adequate ventilation, and storage away from incompatible materials such as strong oxidisers and reducing agents.

Why 2,5-Dichloro Nitro Benzene specifically

• A specific chlorine-nitro relationship. The 2,5-substitution pattern gives reactivity distinct from the other dichloronitrobenzene isomers.
• Dye and pigment intermediate. Feeds dye-intermediate syntheses that require this substitution pattern on the ring.
• Agrochemical building block. A starting material for herbicide and fungicide intermediate routes.
• Pharma intermediate. Used as a building block where reduction to the corresponding dichloroaniline, or direct substitution chemistry, is the required route.

How 2,5-Dichloro Nitro Benzene is Manufactured

2,5-Dichloro Nitro Benzene is produced by nitrating 1,4-dichlorobenzene with mixed acid (nitric/sulfuric) under controlled temperature.

• Nitration. 1,4-Dichlorobenzene is nitrated with mixed acid at a controlled temperature to favour the 2,5-substitution pattern.
• Quench and separation. The crude nitro product is separated from the spent acid phase.
• Wash and purification. The crude is washed and purified to the target assay and melting-point specification.
• Quality release and packing. Assay, melting point and appearance are confirmed against specification before the batch is packed and released.

Typical Commercial Specification

Figures below are representative of commercial-grade 2,5-Dichloro Nitro Benzene. Tell us your downstream route and the grade you need, and we will advise on the specification to order against.

Physical & Chemical Properties

Behaviour in the process

2,5-Dichloro Nitro Benzene's reactivity pattern is what dye, agrochemical and pharma intermediate producers are buying:

• Reducible nitro group. The nitro group is available for reduction to the corresponding 2,5-dichloroaniline.
• Activated ring for substitution. The nitro and chlorine substituents direct further substitution chemistry on the ring.
• Thermal stability. Stable under normal storage conditions away from strong oxidisers and reducing agents.

2,5-DCNB and Related Chloronitrobenzenes

Choosing between dichloronitrobenzene isomers comes down to the position of the two chlorines relative to the nitro group that the target synthesis needs.

Stated plainly: a synthesis built around the 2,5-chlorine pattern needs this specific isomer — other dichloronitrobenzene isomers have different reactivity and are not drop-in substitutes.

Industries We Supply 2,5-Dichloro Nitro Benzene To

The same chloronitrobenzene isomer feeds a dye-intermediate manufacturer, an agrochemical formulator and a pharmaceutical intermediate producer. What changes is the downstream reduction or substitution chemistry and the documentation each requires.

Where 2,5-Dichloro Nitro Benzene is Used

In downstream functionalisation

2,5-Dichloro Nitro Benzene's nitro group is carried through reduction, or the ring is carried through further substitution chemistry, to build the target dye, agrochemical or pharma intermediate. The 2,5-chlorine pattern gives reactivity distinct from other dichloronitrobenzene isomers, which is often exactly why a route is designed around this material specifically.

Quality Control & Testing

Every lot is released against a batch-specific Certificate of Analysis, with melting point and isomer purity reported alongside the main assay because isomer carryover affects downstream reaction selectivity.

• 2,5-DCNB content — by GC assay, the primary grade measure.
• Melting point — reported because it is a sensitive indicator of overall purity for this material.
• Isomer purity — carryover from other dichloronitrobenzene isomers, reported because it affects downstream chemistry.

Common Process Problems & Likely Causes

Packaging, Storage & Shipping

• Standard packing. Multi-ply paper or HDPE-lined bags and fibre drums, typically 25 – 50 kg net, with bulk-bag and bulk formats on contract supply.
• Moisture protection. Keep bags sealed and stored off the floor to limit moisture pickup and caking.
• Temperature control. Store in a cool, dry, well-ventilated area away from direct sun, heat and ignition sources; room temperature storage is standard.
• Material compatibility. Avoid contact with strong oxidisers and strong reducing agents.
• Transport classification. Not universally classified as dangerous goods, but confirm against your own current SDS before finalising shipping paperwork, as treatment can vary by carrier and destination.

Hazards & Safe Handling

2,5-Dichloro Nitro Benzene is harmful if swallowed, in contact with skin or if inhaled, and is harmful to aquatic life with long-lasting effects. Standard precautions for a nitro-aromatic intermediate and good laboratory and plant practice apply throughout handling.

• Skin and eye contact. Chemical-resistant gloves and goggles are standard practice for nitro-aromatic intermediates; rinse thoroughly with water on contact.
• Inhalation. Use adequate ventilation when handling, particularly when transferring or opening bags.
• PPE. Chemical-resistant gloves, safety goggles and, where dust exposure is a concern, a suitable dust mask or respirator.
• Environment. Harmful to aquatic life with long-lasting effects; avoid uncontrolled release to water and follow local effluent rules.

Regulatory & Compliance Notes

2,5-Dichloro Nitro Benzene is a registered specialty nitro-aromatic intermediate. Because obligations differ by territory and use, the notes below are orientation rather than legal advice.

• GHS classification. Classified as harmful if swallowed, in contact with skin or if inhaled, and harmful to aquatic life with long-lasting effects (Signal word: Warning); the SDS carries the full hazard statements for your grade.
• REACH and chemical inventories. Registered under EU REACH and listed on major chemical inventories.
• Dangerous goods transport. Not universally regulated as dangerous goods for this material; confirm the current status with your logistics/EHS team against your current SDS before shipping.
• HS code. Commonly declared under the nitro-derivatives-of-hydrocarbons heading; confirm the exact tariff line with your customs broker for your jurisdiction.

We Supply 2,5-Dichloro Nitro Benzene Worldwide

Chelora Chemicals is a supplier and export partner, not a single-plant trader. We ship 2,5-Dichloro Nitro Benzene from India and from partner sources to customers across Asia, Europe, the Middle East, Africa, and North and South America, handling the export documentation and freight so the material arrives ready to use.

• Incoterms. EXW, FOB, CIF, CFR and DAP quoted to suit your purchasing terms and freight arrangements.
• Ports. Regular shipments through Nhava Sheva (JNPT) and Mundra, with other ports arranged as routing allows.
• Documentation. Commercial invoice, packing list, certificate of origin, COA and SDS issued as a complete set.
• Flexible volumes. From trial quantities up to repeat bulk shipments on a supply contract.

Buying 2,5-Dichloro Nitro Benzene from Chelora

We are an independent sourcing and supply partner. For this product that means settling three things at enquiry: the purity and isomer-purity grade your application needs, the packing format, and the quantity you are buying.

• Documentation on every lot. Batch-specific COA with assay, melting point and isomer breakdown, plus the current SDS.
• Analysis before commitment. Representative analysis shared ahead of a commercial order so your lab can qualify the material.
• Quantities. Trial quantities through to larger bulk shipments on contract supply.
• Inspection. Independent third-party inspection available at loading when the contract requires it.
• Related nitro intermediates. 2,4-Dichloronitrobenzene, para-Nitrochlorobenzene and other chloronitrobenzene isomers alongside this product from one supplier.

How ordering works

• Send the enquiry. Purity, isomer-purity grade, quantity, destination port and the Incoterm you buy on.
• We quote. Price, lead time, packing format and a sample COA, normally within one working day.
• Qualify the supply. For first orders or dye-/agro-/pharma-grade applications, we share the analysis so your technical team can sign off before you commit.
• Confirm the order. Proforma invoice issued; payment terms agreed against the volume and the relationship.
• Ship and document. Packed, labelled and loaded with the full export document set, and tracked through to arrival.

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